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IVD kits for pharmacogenetics

IVD kits for pharmacogenetics

We develop and produce CE IVD real-time PCR kits that are used for in vitro genotypization before an appropiate treatment of disease starts. There application is important at selected drugs where extensive side effects may occur or where various types and speed of metabolism plays a decisive role in treatment.

IVDR

gb PHARM TPMT

gb PHARM TPMT

The CE IVD real-time PCR kit intended for qualitative genotyping of the rs1800462, rs1800460 and rs1142345 polymorphisms in the human gene TPMT encoding the enzyme thiopurine S-methyltransferase. The kit allows the determination of haplotypes TPMT*2, TPMT*3A, TPMT*3B and TPMT*3C in homozygous or heterozygous form.

IVDR

gb PHARM Warfarin

gb PHARM Warfarin

The CE IVD real-time PCR kit is intended for detection of mutation CYP2C9*2, CYP2C9*3 and VKORC1 G1639A in human genomic DNA by real-time PCR method (allelic discrimination).

IVDR

gb PHARM DPYD

gb PHARM DPYD

The CE IVD kit is used for determination of genotype of four polymorphisms according to guidelines CPIC and DPWG: *2A (c1905+1G>A), *13 (c1679T>G), HapB3 (c1236G>A) and c2846A>T in human genomic DNA. The principle of detection is based on real-time PCR with fluorescently labelled probes (allelic discrimination).

IVDR

gb PHARM CYP2C19

gb PHARM CYP2C19

The CE IVD real-time PCR kit is intended for detection of CYP2C19*2, CYP2C19*3 and CYP2C19*17 gene mutation. The detection principle is based on a real-time polymerase chain reaction (qPCR) using fluorescent labeled probes (allelic discrimination).

gb PHARM UGT1A1

gb PHARM UGT1A1

The CE IVD real-time PCR kit allows detection of variants of 5TA (UGT1A1*36), 6TA (UGT1A1*1), 7TA (UGT1A1*28) and 8TA (UGT1A1*37) polymorphisms. The detection is based on the Q-FRET probe and uses the analysis of melting curves for genotyping.

gb PHARM BCHE

gb PHARM BCHE

The CE IVD kit is used for determination of genotype of five polymorphisms: A (D70G, rs1799807), K (A539T, rs1803274), F1 (T243M, rs28933389), F2 (G390V, rs28933390), S1 (FS117, rs398124632) in human genomic DNA.

Oligos with this modification can be inquired or directly ordered using oligo portal.

If you have not been registered in oligo portal, you can make registration here.

Probes of this type can be inquired or directly ordered using oligo portal.

If you have not been registered in oligo portal, you can make registration here.

Oligos with this modification can be ordered only after previous offer. After specific sequences are input to oligo portal (log-in here) we will make an exact offer that you can simply use for your order.

If you have not been registered in oligo portal, you can make registration here.

Probes of this type can be ordered only after previous offer. After specific sequences are input to oligo portal (log-in here) we will make an exact offer that you can simply use for your order.

If you have not been registered in oligo portal, you can make registration here.

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