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modified oligonucleotides

modified oligonucleotides

Modified oligonucleotides – options & examples

Our modified oligonucleotides cover end modifications at the 3′ and 5′ ends as well as internal positions.
We offer base analogs, spacers, fluorophores, quenchers, backbone changes and functional groups for applications such as antisense, sequencing, duplex stabilization, structural studies or click-chemistry conjugations.
All modifications are delivered with high purity and can be combined on request (where chemistry allows).

Popular modifications & use cases

Looking for labeled probes? See
RT-PCR dual-labeled probes
or browse all oligonucleotides.

Thiol S-S

Thiol S-S Thiol S-S

It is used as an intermediate for further oligo modifications (attachment to special surfaces, conjugation). Thiol S-S may be attached to the 5' end of the oligonucleotide.

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Yakima Yellow

Yakima Yellow Yakima Yellow

Yakima Yellow may be attached either to the 5' end or the 3' end of the oligonucleotide.

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SEQplus

SEQplus SEQplus

5´-SEQplus modification of a sequencing primer enables reading of sequence from the 2nd nucleotide of the sequenced DNA. We offer this modification for any user´s sequence or as part of ready-to-use in-stock sequencing primers.

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ATTO dyes

ATTO dyes ATTO dyes

ATTO dyes are a series of fluorescent dyes which provide all the crucial properties required for modern fluorescent technologies with spectral region from 350 nm in the UV to 750 nm in the near infrared.

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