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OLIGO & PROBES

We are an EN ISO 9001, 13485 and 17025 certified EU-located company manufacturing custom DNA oligos. We have been synthesizing custom DNA oligonucleotides since 1995. Every year our custom oligo synthesis services produce dozens of thousands of oligos in many categories: unmodified oligos, variously modified oligos, oligos with various types of purifications and for various purposes (biological techniques based mostly on PCR, NGS, biophysical studies etc.). We produce real-time PCR probes as well.

The know-how we acquired in custom DNA oligo synthesis during the last 25 years is implemented into the development of other products, especially CE IVD kits and Life Sciences products.

Our typical partners are end-users of the custom DNA oligos (customers mostly in CZ and SK), business partners and distributors mostly within EU. We are looking for business partners and/or distributors worldwide who can fit the portfolio of our products, either the whole or a part of it, into their sales strategy.

BHQ3

BHQ3 BHQ3

Quencher suitable for fluorophores having an emission wavelength range from 620 to 730 nm. BHQ3 may be attached to the 3'end of the oligonucleotide.

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BHQ2

BHQ2 BHQ2

A quencher suitable for fluorophores having an emission wavelength range from 540 to 670 nm. BHQ2 may be attached anywhere within the oligonucleotide sequence.

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BHQ1

BHQ1 BHQ1

A quencher suitable for fluorophores having an emission wavelength range from 480 to 580 nm. BHQ1 may be attached anywhere within the oligonucleotide sequence.

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Cy3.5

Cy3.5 Cy3.5

May be attached anywhere within the oligonucleotide sequence except for the 3' end.

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Dy647

Dy647 Dy647

May be attached to the 5' end of the oligonucleotide. Oligonucleotide purification is a necessity.

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Dy547

Dy547 Dy547

May be attached to the 5' end of the oligonucleotide.

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Yakima Yellow

Yakima Yellow Yakima Yellow

Yakima Yellow may be attached either to the 5' end or the 3' end of the oligonucleotide.

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JOE

JOE JOE

6-karboxy-4', 5'-dichlor-2', 7'-dimethoxyfluorescein is commonly used in multiplex reactions together with FAM. JOE may be attached to the 5' end of the oligonucleotide.

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Thiol S-S

Thiol S-S Thiol S-S

It is used as an intermediate for further oligo modifications (attachment to special surfaces, conjugation). Thiol S-S may be attached to the 5' end of the oligonucleotide.

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Thiol SH

Thiol SH Thiol SH

It is used as an intermediate for further oligo modifications (attachment to special surfaces, conjugation) and as a blocker of 3' polymerase extension. Thiol SH may be attached either to the 5' end or the 3' end of the oligonucleotide.

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CFR 635

CFR 635 CFR 635

CFR 635 is an orange-red fluorophore. It is used as a good alternative to LC red 640. CFR 635 may be attached only to 5´end of an oligonucleotide.

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Biotin

Biotin Biotin

Biotin may be attached either to the 5' end or the 3' end of the oligonucleotide. The biotin molecule is separated from the 3' end by a sixteen carbon spacer.

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