Info Example of selection
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list of genes
Function | # | Gene Symbol | Gene Name | Description | GeneBank |
iPSC Markers | 1 | DNMT3B | ICF, ICF1, M.HsaIIIB | DNA (cytosine-5-)-methyltransferase 3 beta | NM_006892 |
2 | PODXL | Gp200, PC, PCLP, PCLP-1 | Podocalyxin-like | NM_005397 | |
3 | ZFP42 | REX1, ZNF754 | Zinc finger protein 42 homolog (mouse) | NM_174900 | |
Other iPSC-Related Genes: | 4 | ACTC1 | ACTC, ASD5, CMD1R, CMH11, LVNC4 | Actin, alpha, cardiac muscle 1 | NM_005159 |
5 | BRIX1 (BXDC2) | BRIX, BXDC2 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae) | NM_018321 | |
6 | CD9 | BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29 | CD9 molecule | NM_001769 | |
7 | COL2A1 | ANFH, AOM, COL11A3, SEDC, STL1 | Collagen, type II, alpha 1 | NM_001844 | |
8 | FGF4 | HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF | Fibroblast growth factor 4 | NM_002007 | |
9 | FOXD3 | AIS1, Genesis, HFH2, VAMAS2 | Forkhead box D3 | NM_012183 | |
10 | GABRB3 | ECA5 | Gamma-aminobutyric acid (GABA) A receptor, beta 3 | NM_000814 | |
11 | GRB7 | – | Growth factor receptor-bound protein 7 | NM_005310 | |
12 | LEFTY1 | LEFTB, LEFTYB | Left-right determination factor 1 | NM_020997 | |
13 | NODAL | HTX5 | Nodal homolog (mouse) | NM_018055 | |
14 | REST | NRSF, XBR | RE1-silencing transcription factor | NM_005612 | |
15 | RUNX2 | AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA | Runt-related transcription factor 2 | NM_004348 | |
16 | TERT | CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT | Telomerase reverse transcriptase | NM_198253 | |
17 | ALDH1A1 | ALDC, ALDH-E1, ALDH1, ALDH11, HEL-S-53e, HEL12, PUMB1, RALDH1 | Aldehyde dehydrogenase 1 family, member A1 | NM_000689 | |
18 | ALDH2 | ALDH-E2, ALDHI, ALDM | Aldehyde dehydrogenase 2 family (mitochondrial) | NM_000690 | |
19 | APC | BTPS2, DP2, DP2.5, DP3, GS, PPP1R46 | Adenomatous polyposis coli | NM_000038 | |
20 | CDH2 | CD325, CDHN, CDw325, NCAD | Cadherin 2, type 1, N-cadherin (neuronal) | NM_001792 | |
21 | FGFR1 | BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1 | Fibroblast growth factor receptor 1 | NM_015850 | |
22 | HDAC2 | HD2, RPD3, YAF1 | Histone deacetylase 2 | NM_001527 | |
23 | KAT2A | GCN5, GCN5L2, PCAF-b, hGCN5 | K(lysine) acetyltransferase 2A | NM_021078 | |
24 | KAT7 | HBO1, HBOA, MYST2, ZC2HC7 | K(lysine) acetyltransferase 7 | NM_007067 | |
25 | KAT8 | MOF, MYST1, ZC2HC8, hMOF | K(lysine) acetyltransferase 8 | NM_032188 | |
26 | PARD6A | PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40 | Par-6 partitioning defective 6 homolog alpha (C. elegans) | NM_016948 | |
27 | COMMD3 | BUP, C10orf8, RP11-573G6.3 | COMM domain containing 3 | NM_012071 | |
28 | IL6ST | CD130, CDW130, GP130, IL-6RB | interleukin 6 signal transducer (gp130, oncostatin M receptor) | NM_175767 | |
29 | LIFR | CD118, LIF-R, SJS2, STWS, SWS | leukemia inhibitory factor receptor alpha | NM_002310 | |
30 | SFRP2 | FKSG12, FRP-2, SARP1, SDF-5 | secreted frizzled-related protein 2 | NM_003013 | |
Reprogramming Factors | 31 | POU5F1 (Oct3/4) | OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4 | POU class 5 homeobox 1 | NM_002701 |
32 | SOX2 | ANOP3, MCOPS3 | SRY (sex determining region Y)-box 2 | NM_003106 | |
33 | KLF4 | EZF, GKLF | Kruppel-like factor 4 (gut) | NM_004235 | |
Other Reprogramming Factors: | 34 | LIN28A | CSDD1, LIN-28, LIN28, ZCCHC1, lin-28A | Lin-28 homolog A (C. elegans) | NM_024674 |
35 | NANOG | – | Nanog homeobox | NM_024865 | |
36 | NR5A2 | B1F, B1F2, CPF, FTF, FTZ-F1, FTZ-F1beta, LRH-1, LRH1, hB1F-2 | Nuclear receptor subfamily 5, group A, member 2 | NM_003822 | |
Reprogramming Enhancers & Inhibitors: | 37 | UTF1 | – | Undifferentiated embryonic cell transcription factor 1 | NM_003577 |
ESC Markers: | 38 | ALPL | AP-TNAP, APTNAP, HOPS, TNAP, TNSALP | Alkaline phosphatase, liver/bone/kidney | NM_000478 |
39 | GDF3 | KFS3, MCOP7, MCOPCB6 | Growth differentiation factor 3 | NM_020634 | |
40 | TDGF1 (CRIPTO) | CR, CRGF, CRIPTO | Teratocarcinoma-derived growth factor 1 | NM_003212 | |
Other ESC-Related Genes: . | 41 | CCNA2 | CCN1, CCNA | Cyclin A2 | NM_001237 |
42 | CDK1 (CDC2) | CDC2, CDC28A, P34CDC2 | Cyclin-dependent kinase 1 | NM_001786 | |
43 | CDC42 | CDC42Hs, G25K | Cell division cycle 42 (GTP binding protein, 25kDa) | NM_001791 | |
44 | DPPA2 | CT100, ECAT15-2, PESCRG1 | Developmental pluripotency associated 2 | NM_138815 | |
45 | DPPA3 | STELLA | Developmental pluripotency associated 3 | NM_199286 | |
46 | FGF2 | BFGF, FGF-2, FGFB, HBGF-2 | Fibroblast growth factor 2 (basic) | NM_002006 | |
47 | HSPA9 | CSA, GRP-75, GRP75, HSPA9B, MOT, MOT2, MTHSP75, PBP74 | Heat shock 70kDa protein 9 (mortalin) | NM_004134 | |
48 | MYBL2 | B-MYB, BMYB | V-myb myeloblastosis viral oncogene homolog (avian)-like 2 | NM_002466 | |
49 | OTX2 | CPHD6, MCOPS5 | Orthodenticle homeobox 2 | NM_021728 | |
50 | SOX15 | SOX20, SOX26, SOX27 | SRY (sex determining region Y)-box 15 | NM_006942 | |
51 | TBX3 | TBX3-ISO, UMS, XHL | T-box 3 | NM_016569 | |
52 | TCF3 | E2A, E47, ITF1, TCF-3, VDIR, bHLHb21 | Transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | NM_003200 | |
Keratinocyte: | 53 | CDH1 | Arc-1, CD324, CDHE, ECAD, LCAM, UVO | Cadherin 1, type 1, E-cadherin (epithelial) | NM_004360 |
54 | GJB2 | CX26, DFNA3, DFNA3A, DFNB1, DFNB1A, HID, KID, NSRD1, PPK | Gap junction protein, beta 2, 26kDa | NM_004004 | |
55 | KRT15 | CK15, K15, K1CO | Keratin 15 | NM_002275 | |
56 | NUMB | C14orf41, S171, c14_5527 | Numb homolog (Drosophila) | NM_003744 | |
Blood Stem Cell: | 57 | CD34 | – | CD34 molecule | NM_001773 |
Fibroblast: | 58 | COL1A1 | OI4 | Collagen, type I, alpha 1 | NM_000088 |
59 | NCAM1 | CD56, MSK39, NCAM | Neural cell adhesion molecule 1 | NM_000615 | |
Neuronal Stem Cell: | 60 | EMX2 | – | Empty spiracles homeobox 2 | NM_004098 |
61 | FABP7 | B-FABP, BLBP, FABPB, MRG | Fatty acid binding protein 7, brain | NM_001446 | |
62 | NES | – | Nestin | NM_006617 | |
63 | OLIG2 | BHLHB1, OLIGO2, PRKCBP2, RACK17, bHLHe19 | Oligodendrocyte lineage transcription factor 2 | NM_005806 | |
Cardiomyocyte | 64 | PECAM1 | CD31, CD31, EndoCAM, GPIIA‘, PECA1, PECAM-1, endoCAM | Platelet/endothelial cell adhesion molecule | NM_000442 |
Germ Cells | 65 | SYCP3 | COR1, SCP3, SPGF4 | Synaptonemal complex protein 3 | NM_153694 |
Ectoderm: | 66 | PAX6 | AN, AN2, D11S812E, MGDA, WAGR | Paired box 6 | NM_000280 |
67 | TUBB3 | CDCBM, CDCBM1, CFEOM3A, TUBB4, beta-4 | Tubulin, beta 3 | NM_006086 | |
68 | FGF8 | AIGF, FGF-8, HBGF-8, HH6, KAL6 | fibroblast growth factor 8 (androgen-induced) | NM_006119 | |
69 | BMP4 | BMP2B, BMP2B1, MCOPS6, OFC11, ZYME | Bone morphogenetic protein 4 | NM_001202 | |
70 | FN1 | CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF | fibronectin 1 | NM_212482.1 | |
71 | GFAP | glial fibrillary acidic protein | NM_002055 | ||
72 | NEUROD1 | BETA2, BHF-1, MODY6, NEUROD, bHLHa3 | neuronal differentiation 1 | NM_002500 | |
73 | TH | DYT14, DYT5b, TYH | tyrosine hydroxylase | NM_199293 | |
Mesoderm:. | 74 | GATA2 | DCML, MONOMAC, NFE1B | GATA binding protein 2 | NM_032638 |
75 | HAND1 | Hxt, Thing1, bHLHa27, eHand | Heart and neural crest derivatives expressed 1 | NM_004821 | |
76 | MESP1 | bHLHc5 | Mesoderm posterior 1 homolog (mouse) | NM_018670 | |
77 | HBB | CD113t-C, beta-globin | hemoglobin, beta | NM_000518 | |
78 | RUNX1 | AML1, AML1-EVI-1, AMLCR1, CBFA2, EVI-1, PEBP2aB | Runt-related transcription factor 1 | NM_001754 | |
Endoderm: | 79 | FOXA2 | HNF3B, TCF3B | Forkhead box A2 | NM_021784 |
80 | GATA4 | ASD2, TACHD, VSD1 | GATA binding protein 4 | NM_002052 | |
81 | HNF4A | HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14 | Hepatocyte nuclear factor 4, alpha | NM_178849 | |
82 | SOX17 | VUR3 | SRY (sex determining region Y)-box 17 | NM_022454 | |
83 | EOMES | TBR2 | eomesodermin | NM_005442.2. |