Contamination by production organism residual DNA
Plasmid DNA is frequently used in gene therapy and high purity plasmids are required. Residual DNA or proteins from the production organism (where plasmid was produced e.g. E. coli) are considered unacceptable contaminant.
Contamination by wild type virus in artificial drug virus
Viral vaccines or vectors are mostly prepared from wild type precursors, which lost their original activity. Artificial virus is less dangerous than wild type and has special characteristics. Wild type virus in a vaccine could have dangerous effect.
Viral contaminants in virus-free material
For the control of biological material it is necessary to check if the material does not contain any hazardous biological substance, such as virus.
Contamination tests on request development of method and subsequent validation can be included
Izolační kit umožňuje získat vysoce čistou genomovou DNA ze vzorků plné krve, séra, plazmy, ze stěrů bukální sliznice a z moči. Z těchto typů matrice lze navíc velmi účinně izolovat i virovou DNA. Kit zaručuje vysoké výtěžky DNA, reprodukovatelné výsledky a rychlý pracovní postup.
Why choose alternative dyes instead of "genuine" dyes? First, they are cheaper, and second, they can give the same results. Another reason is that the number of suppliers who can provide modified oligonucleotides is restricted - only a patent or a licence owner is usually allowed to produce them.