All medical devices, even when used appropriately, present a certain degree of risk to patients. Therefore, they have to be evaluated for their biocompatibility according to international harmonized standard ISO 10993-5 – Biological evaluation of medical devices, Part 5: Test for In Vitro Cytotoxicity.
Cell proliferation test / cytotoxicity test
Cytotoxicity tests can be widely used in assessment of chemically induced substance toxicity. As a part of our biotechnological services we offer standard XTT test, which is performed on eukaryotic cell lines.
Test is performed according to the EN ISO 10993-5, and can be performed on a wide range of materials: from usual soluble, solid or liquid substances, to preparation of a leach from insoluble substances. The test may be applied in pharmaceutical research, in medical products testing, in cosmetics, and in testing of material compatibility for tissue cultures.
We perform assessment of cytotoxicity either through viability measuring or through determination of IC50 value, according to the type of material and customer’s requirements.