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Cell proliferation test / cytotoxicity test

Cell proliferation test / cytotoxicity test

Cytotoxicity tests can be widely used in assessment of chemically induced substance toxicity. As a part of our biotechnological services we offer standard XTT test, which is performed on eukaryotic cell lines.

Test is performed according to the EN ISO 10993-5, and can be performed on a wide range of materials: from usual soluble, solid or liquid substances, to preparation of a leach from insoluble substances. The test may be applied in pharmaceutical research, in medical products testing, in cosmetics, and in testing of material compatibility for tissue cultures.

We perform assessment of cytotoxicity either through viability measuring or through determination of IC50 value, according to the type of material and customer’s requirements.

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Much like typical chemical compounds, nucleic acid gene therapy agens, such as plasmids/vectors, viral particles and other, need quality control as well. Mostly it is a detection of unwanted contaminants what is needed. These contaminants originate from production systems where DNA was prepared, either from a cultivation media or as natural contaminants or from the changed original molecule.

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