Food and feed testing services

Although food and feed testing does not fall into pharma testing, some QC tests are based on similar techniques and methods as those used in Good Manufacturing Practice.

European Food Safety Authority (EFSA) requires many QC processes before food or feed is released to the market. Some of them are based on DNA/RNA testing and they are very similar to those we provide in the scope of pharma testing, such as: DNA/RNA based detection of biological hazards, detection of DNA contaminants in feed additives, detection of genetically modified (GM) food or feed.

There are two main areas where GENERI BIOTECH can provide an impact:

The first area is the testing itself, especially when a method used is complicated and may not be performed efficiently on a routine basis.

The other area is the development of methods and tools for effective routine testing in manufacturer´s laboratory.

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gb SG PCR Master Mix

gb SG PCR Master Mix falls into a group of Real-Time PCR Master Mixes to provide Dye-based qPCR. The product consists of hot-start Taq DNA polymerase, reaction buffer, dNTP, MgCl2, sybrgreen and additives that prevent PCR inhibition. Taq polymerase is chemically modified DNA polymerase from Thermus aquaticus. This polymerase is completely inactive at room temperature but it is rapidly activated during the initial denaturation step of PCR.

Alternative dyes for oligonucleotides/probes labeling

Why choose alternative dyes instead of "genuine" dyes? First, they are cheaper, and second, they can give the same results. Another reason is that the number of suppliers who can provide modified oligonucleotides is restricted - only a patent or a licence owner is usually allowed to produce them.

CRO case studies

Yeast Production Strain Cell Line Authentication by RFLP analysis

Background Probiotics are defined as live microorganisms which, when administered in adequate amounts, confer a health benefit on the host. For instance, probiotics can be used in the treatment and prevention of infections and chronic inflammatory disorders of the gastrointestinal tract. Due to their health attributes, probiotics generate considerable interest in the area of functional

CRO case studies

Quality Control Check of Avermectin Batches for Presence of Residual DNA

The avermectins compose a class of polycyclic lactones that are used to treat parasitic worms and insect pests. They are naturally occurring compounds generated in a fermentation process by a soil actinomycete Streptomyces avermitilis.

CRO case studies

GLP-compliant Biodistribution Study of Vaccinia Virus in Mice by qPCR

Biodistribution (BD) studies are critical components when assessing the preclinical safety evaluation of cell and gene therapy molecules. BD analysis is generally conducted at the molecular level using a methodology that provides high sensitivity.