gb GENETIC HLA-B*27
The kit is intended for detection of HLA-B27 allele in samples of human DNA. Detection principle is based on real-time PCR method with allele specific primers and fluorescently labeled hydrolyzation probes.
The presence of B27 antigen (HLA-B27) is strongly associated with ankylosing spondylitis (AS) and other inflammatory disorders. The frequency of HLA-B*27 allele in Caucasian population is in range 5–10% and in AS-patients occurs in more than 85% cases. The absence of HLA-B27 allele is a strong negative predictor for diagnosis of AS.
Parameters of the diagnostic kit
- in vitro diagnostics
- CE IVD marked
- ready-to-use assay
- sample concentration 1-100 ng/µl
- positive and negative controls included
- FAM and HEX channels detection
- identical amplification profile as gb HEMO, gb GENETIC, gb PHARM kits