gb Human B2M mRNA
one-step real-time PCR
The gb Human B2M mRNA kit enables the detection of human mRNA. Detection is based on the B2M gene (Gene ID 567). This gene encodes beta-2-microglobulin. It is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells (excludes red blood cells). The kit is intended to monitor the quality of RNA isolates from human biological material.
Purpose of the test
The kit is intended for those labs that need to confirm the quality of the analyzed sample to prevent false negative results. It enables to check both, if swab samples have been collected efficiently and if RNA extraction method works efficiently as well.
Using the gb Human B2M mRNA kit the whole preanalytical process is checked, typically when detection of SARS-CoV-2 viral RNA is provided. In case that any sample deviates from the series (or it is not detected at all), new collection and reanalysis of the sample is recommended.