Opportunistic infections caused by Aspergillus species are responsible for frequent therapy complications in an increasing number of immuno-compromised patients (involves especially
patients after hematopoietic cell or solid organ transplantation, patients with hematological malignancies or other diseases related to the malfunction of the immune system).
This type of infection is mostly manifested as invasive aspergillosis (IA). Early diagnosis and efficient antimycotic treatment is most important for the patient’s survival.. The infection usually attacks the respiratory system and that is why IA mostly affects lungs (or less frequently paranasal sinuses and CNS (brain)). In the case of dissemination process, almost every organ (gastrointestinal tract, heart, kidneys) may be affected. Most cases of IA (approximately 80 %) are caused by the species Aspergillus fumigatus, other clinically important species are A. flavus, A. niger, A. terreus, other Aspergillus species occur rarely.
Parameters of the real-time PCR diagnostic kit
- ready-to-use assays
- LOD 0.7 copies/µl
- internal positive control, standards and negative control included
- fungal DNA detection in FAM channel