Herpes simplex virus 2 (HSV2) is an enveloped DNA-virus of Herpesviridae family belonging to the Simplexvirus genus. For these viruses a short replication time and the ability to
trigger latent infection of cells is typical. HSV2 virus enters the human body through the mucosis of the genitals. The virus proliferates in the entrance gate and extends further on to the nerve endings.
Then it arrives in the ganglia cells by axonal transport where it lasts for practically the whole life. Reactivation of infection and repetitive proliferation of the virus, so called recurrent infection, can happen under the influence of different types of stress (fever, hormonal influences, insolation etc). Primary infection triggered by HSV2 virus is demonstrated in adults as herpes genitalis, it can occur as generalized herpes with afflictions of the skin, brain, liver and lungs of newly born babies of non immune mothers. The course of recurrent infection of HSV2 is usually much milder than at the primary infection.
Parameters of the real-time PCR diagnostic kit
- ready-to-use assays
- LOD 0.57 copies/µl
- internal positive control, standards and negative control included
- FAM channel detection
- internal positive control in HEX channel