gb ONCO BCR-ABL MICRO / ABL
one-step real-time PCR
This in vitro diagnostic kit enables the quantitative determination of the copy number ratio of the e19a2 (c3a2) transcript of the BCR-ABL1 fusion gene to the copy number of the ABL1 reference gene transcript.
Clinical implications of the CE IVD kit
The BCR-ABL1 fusion gene in the rare MICRO variant occurs in patients with chronic neutrophilic leukemia (CML-N). Patient response to treatment as well as minimal residual disease is monitored by quantification of BCR-ABL1 transcript relative to control gene transcript (ABL1).
Parameters of the real-time PCR diagnostic kit
- detection in the FAM (BCR-ABL1) channel and HEX (ABL1) channel
- calibrating panel of standards and no template control included
ABI 7500/7500 Fast (ABI)
Light Cycler 480/Cobas z480 (Roche Diagnostics)
QuantStudio 7 (Applied Biosystems)
RG 3000 (Corbett Research)