The technology of dual-labeled hydrolysis probes (also called TaqMan® real-time PCR probes) exploits the 5 ́-3 ́ exonuclease activity of Taq DNA polymerase to cleave the probe. TaqMan real-time PCR probes are labeled with a fluorescent dye (reporter) at the 5´ end and with a quencher at the 3´ end.
gb ONCO BCR-ABL MICRO / ABL
Detection method: one-step real-time PCR
This in vitro diagnostic kit enables the quantitative determination of the copy number ratio of the e19a2 (c3a2) transcript of the BCR-ABL1 fusion gene to the copy number of the ABL1 reference gene transcript.
Clinical implications of the CE IVD kit
The BCR-ABL1 fusion gene in the rare MICRO variant occurs in patients with chronic neutrophilic leukemia (CML-N). Patient response to treatment as well as minimal residual disease is monitored by quantification of BCR-ABL1 transcript relative to control gene transcript (ABL1).
Parameters of the real-time PCR diagnostic kit
- detection in the FAM (BCR-ABL1) channel and HEX (ABL1) channel
- calibrating panel of standards and no template control included
|Cat. No.||Product||No. of reactions||Price|
|3248-048||gb ONCO BCR-ABL MICRO / ABL||48||
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1 CE IVD one-step real-time PCR kit contains reagents to provide 48 PCR reactions (25 μl volume of each reaction).
Shiping on dry ice from
€ 100 (EU)
For other destinations see indicative list.
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