gb ONCO BCR-ABL MINOR / ABL
one-step real-time PCR
gb ONCO BCR-ABL MINOR / ABL enables the quantitative determination of the copy number ratio of the e1a2 transcript of the BCR-ABL1 fusion gene to the copy number of the ABL1 reference gene transcript.
The BCR-ABL1 fusion gene in the rare MINOR variant occurs in patients with chronic myeoloid leukemia (CML) and Ph+ acute lymphoblastic leukemia (ALL). Patient response to treatment as well as minimal residual disease is monitored by quantification of BCR-ABL1 transcript relative to control gene transcript (ABL1). The kit is intended for in vitro diagnostic use.
Parametres of the diagnostic kit
- detection in the FAM (BCR-ABL1) channel and HEX (ABL1) channel