gb MICRO Aspergillus

gb MICRO Aspergillus

Detection method: quantitative real-time PCR

The purpose of the kit is the detection and quantification of the pathogenic DNA of the most commonly occurring species of Aspergillus – Aspergillus fumigatus, Aspergillus flavus, Aspergillus niger and Aspergillus terreus by real-time PCR method.

Clinical implications

Opportunistic infections caused by Aspergillus species are responsible for frequent therapy complications in an increasing number of immuno-compromised patients (involves especially patients after hematopoietic cell or solid organ transplantation, patients with hematological malignancies or other diseases related to the malfunction of the immune system).

This type of infection is mostly manifested as invasive aspergillosis (IA). Early diagnosis and efficient antimycotic treatment is most important for the patient’s survival. The infection usually attacks the respiratory system and that is why IA mostly affects lungs (or less frequently paranasal sinuses and CNS (brain)). In the case of dissemination process, almost every organ (gastrointestinal tract, heart, kidneys) may be affected. Most cases of IA (approximately 80 %) are caused by the species Aspergillus fumigatus, other clinically important species are A. flavus, A. niger, A. terreus, other Aspergillus species occur rarely.

Parameters of the diagnostic kit

  • ready-to-use assays
  • LOD 0.19-9.10 copies/µl
  • internal positive control, standards and negative control included
  • fungal DNA detection in FAM channel
Cat. No. Product No. of tests Price
3222-025 gb MICRO Aspergillus 25
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1 kit contains 4 assays for 25 PCR reactions (20 μl volume of each reaction).

Validated for:

ABI 7900HT (ABI)

AriaMx (Agilent Technologies)

CFX96/96Touch (Bio-Rad)

MIC (BMS)

RG 3000 (Corbett Research)

RG 6000/Q (Corbett Research/Qiagen)

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