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IVD kits for oncology

IVD kits for oncology

ngs ONCO anti-EGFR ngs ONCO anti-EGFR

ngs ONCO anti-EGFR ngs ONCO anti-EGFR

DNA samples are prepared in a two-step PCR amplification. Target hotspot regions are amplified during the 1st multiplex PCR reaction and sample specific molecular barcodes are added in the 2nd universal PCR amplification.

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gb ONCO BCR-ABL MAJOR gb ONCO BCR-ABL MAJOR

gb ONCO BCR-ABL MAJOR gb ONCO BCR-ABL MAJOR

Real-time PCR diagnostic kit enables detection and quantification of the major transcripts of b2a2 and b3a2 of the abberant chromosome BCR-ABL1. The examination is based on one-step RT-qPCR using fluorescently labeled probes. Quantification of both fusion and reference transcript is processed in one tube.

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gb ONCO BCR-ABL MINOR / ABL gb ONCO BCR-ABL MINOR / ABL

gb ONCO BCR-ABL MINOR / ABL gb ONCO BCR-ABL MINOR / ABL

gb ONCO BCR-ABL MINOR / ABL enables the quantitative determination of the copy number ratio of the e1a2 transcript of the BCR-ABL1 fusion gene to the copy number of the ABL1 reference gene transcript.

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gb ONCO BCR-ABL MICRO / ABL gb ONCO BCR-ABL MICRO / ABL

gb ONCO BCR-ABL MICRO / ABL gb ONCO BCR-ABL MICRO / ABL

gb ONCO BCR-ABL MICRO / ABL enables the quantitative determination of the copy number ratio of the e19a2 (c3a2) transcript of the BCR-ABL1 fusion gene to the copy number of the ABL1 reference gene transcript.

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gb ONCO BCR-ABL DETECT gb ONCO BCR-ABL DETECT

gb ONCO BCR-ABL DETECT gb ONCO BCR-ABL DETECT

gb ONCO BCR-ABL DETECT is intended for a qualitative determination of a type of the BCR-ABL1 fusion gene alteration. Apart from commonly occurring fusions the kit detects rare alterations as well. Detection method based on one-step RT-qPCR ensures quick, less laborious and, above all, semiquantitative determination of the fusion type, while sophisticated system of controls ensures validity of the result and its adequate interpretation.

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STANDARD MMR BCR-ABL MAJOR STANDARD MMR BCR-ABL MAJOR

STANDARD MMR BCR-ABL MAJOR STANDARD MMR BCR-ABL MAJOR

STANDARD MMR BCR-ABL MAJOR is an RNA standard representing a defined ratio of BCR-ABL1 in MAJOR (b3a2) on the background of the ABL1 and GUSB reference gene at the major molecular response level (MMR). To convert the BCR-ABL1 MAJOR results to IS, it is necessary to include the STANDARD in to the own analysis and the results analysis.

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gb ONCO JAK2 (V617F)

gb ONCO JAK2 (V617F) gb ONCO JAK2 (V617F)

The kit is used for detection and quantification of somatic mutation V617F JAK2 gene in human genomic DNA. The detection principle is based on real-time PCR using fluorescently labeled probes and allele specific primers.

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gb ONCO BRAF (V600E) gb ONCO BRAF (V600E)

gb ONCO BRAF (V600E) gb ONCO BRAF (V600E)

The kit is used to detect and quantify the BRAF V600E, E2, D somatic mutation in human genomic DNA. The detection principle is based on real-time polymerase chain reaction (qPCR) using fluorescently labeled probes and allele specific primers.

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gb ONCO CLL gb ONCO CLL

gb ONCO CLL gb ONCO CLL

Kit is intended for prognosis assessment in CLL patients by analysis of cDNA (reverse transcribed RNA) samples of human B lymphocytes obtained from peripheral blood. The kit is based on reverse transcription together with quantitative real-time polymerase chain reaction (qRT-PCR) using fluorescently labelled probes.

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