Categories

Phosphorothioates

Phosphorothioates

Modification by group: Modified backbone

Position of modification: internal

Phosphorothioates contain the exchange of one oxygen in the phosphate bond with sulfur. By exchanging oxygen for sulfur, the resistance of the oligonucleotide to nucleases increases.


pure phosphorothioates: substitution is made in all phosphate linkages in the chain
mixed phosphorothioates: substitution is only made on selected phosphate bonds.

Phosphorothioates are used for antisense applications where a 10 μmol scale is usually selected.

Cat. No. Modification Scale Price
1160-020 Phosphorothioates 20 nmol
Add to Quote
Add to Quote
1160-040 Phosphorothioates 40 nmol
Add to Quote
Add to Quote
1160-200 Phosphorothioates 200 nmol
Add to Quote
Add to Quote
1160-001 Phosphorothioates 1 micromol
Add to Quote
Add to Quote
1160-010 Phosphorothioates 10 micromol
Add to Quote
Add to Quote

Oligo price = price of sequence without modification + surcharge for modification

Shiping at ambient temperature from € 40 (EU)
For other destinations see indicative list.

General Terms and Conditions

Useful links
Recommended products
gb SG PCR Master Mix

gb SG PCR Master Mix gb SG PCR Master Mix

gb SG PCR Master Mix falls into a group of Real-Time PCR Master Mixes to provide Dye-based qPCR. The product consists of hot-start Taq DNA polymerase, reaction buffer, dNTP, MgCl2, sybrgreen and additives that prevent PCR inhibition. Taq polymerase is chemically modified DNA polymerase from Thermus aquaticus. This polymerase is completely inactive at room temperature but it is rapidly activated during the initial denaturation step of PCR.

More
Recommended articles